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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MMP2, matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
Sequence ID:NM_001127891
NM_004530
RefSeqGene ID:NG_008989
Entrez Gene ID:4313
Ensembl ID:ENSG00000087245

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
TORG-WINCHESTER SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:16q13-q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 55520529 - 55522681

 Exon Info From UCSC:
NM_001127891
NM_004530

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3161383Full LengthBC002576matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004521  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001127891 NP_001121363      
NM_004530 NP_004521 P08253 EC 3.4.24.24 fn2
Hemopexin
Peptidase_M10
PG_binding_1

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
J03210 AAA35701 P08253 EC 3.4.24.24
BC002576 AAH02576 P08253 EC 3.4.24.24
DQ385623 ABD38929 Q2EF79  
DQ891952 ABM82878    
DQ895138 ABM86064    
AK312711 BAG35588 P08253 EC 3.4.24.24
AK301536 BAG63035 B4DWH3  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MMP2 NP_004521 M.musculus Mmp2 17390 Gene Info NP_032636 96
R.norvegicus Mmp2 81686   NP_112316 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta