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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FURIN, furin (paired basic amino acid cleaving enzyme)
Sequence ID:NM_002569
Entrez Gene ID:5045
Ensembl ID:ENSG00000140564

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q26.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 91422033 - 91423214

 Exon Info From UCSC:
NM_002569

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4550620Full LengthBC012181furin (paired basic amino acid cleaving enzyme)
4025492IncompleteBC008295furin (paired basic amino acid cleaving enzyme)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002560  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002569 NP_002560 P09958 EC 3.4.21.75 Peptidase_S8
P_proprotein

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
S65442 AAB28140    
BC012181 AAH12181 P09958 EC 3.4.21.75
X17094 CAA34948 P09958 EC 3.4.21.75

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FURIN NP_002560 M.musculus Furin 18550 Gene Info NP_001074923 94
R.norvegicus Furin 54281   NP_062204 94
A.gambiae AgaP_AGAP001330 1281848   XP_321814 61
C.elegans kpc-1 173051   NP_492974 61

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta