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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TK2, thymidine kinase 2, mitochondrial
Sequence ID:NM_001172643
NM_001172644
NM_001172645
NM_004614
RefSeqGene ID:NG_016862
Entrez Gene ID:7084
Ensembl ID:ENSG00000166548

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MITOCHONDRIAL DNA DEPLETION SYNDROME 2 (MYOPATHIC TYPE)SUCLA2

Cytogenetic Location (from UniGene)

Cytogenetic Location:16q22-q23.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 66503746 - 66551105

 Exon Info From UCSC:
NM_001172643
NM_001172644
NM_001172645
NM_004614

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8860391Full LengthBC142970thymidine kinase 2, mitochondrial
4812465IncompleteBC040667thymidine kinase 2, mitochondrial
40031856IncompleteBC134344thymidine kinase 2, mitochondrial
40031861IncompleteBC113928thymidine kinase 2, mitochondrial

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004605  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001172643 NP_001166114      
NM_001172644 NP_001166115      
NM_001172645 NP_001166116      
NM_004614 NP_004605 Q8IZR3
O00142
EC 2.7.1.21 dNK

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U77088 AAC51167 O00142 EC 2.7.1.21
U80628 AAC51168 Q6I8R3  
BC134344 AAI34345 A4IF54  
BC142970 AAI42971 A5PLM0  
AF521891 AAN73847 Q8IZR3  
AK294627 BAG57808 O00142 EC 2.7.1.21
AK295808 BAG58626 B4DIW4  
AK302976 BAG64119 B4DZK7  
AK303590 BAG64606 B4E0Z4  
AK316226 BAH14597 O00142 EC 2.7.1.21
Y10498 CAA71523 O00142 EC 2.7.1.21

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TK2 NP_004605 R.norvegicus Tk2 291824   NP_001099636 82
M.musculus Tk2 57813 Gene Info NP_066356 82
A.gambiae AgaP_AGAP001585 1281587   XP_321524 50
D.melanogaster dnk 42273   NP_524399 46

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)