Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CDKN2A, cyclin-dependent kinase inhibitor 2A
Sequence ID:NM_000077
NM_001195132
NM_058195
NM_058197
NM_058196
RefSeqGene ID:NG_007485
Entrez Gene ID:1029
Ensembl ID:ENSG00000147889

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
LI-FRAUMENI SYNDROMETP53
TP53
MELANOMA AND NEURAL SYSTEM TUMOR SYNDROME 
MELANOMA, CUTANEOUS MALIGNANT, 2 
PANCREATIC CANCER/MELANOMA SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:9p21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 21968178 - 21974826

 Exon Info From UCSC:
NM_000077
NM_058195
NM_058197

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2988668IncompleteBC021998cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
3954155IncompleteBC015960cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_478102  NP_000068  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000077 NP_000068 P42771 Ank
NM_001195132 NP_001182061    
NM_058195 NP_478102 Q8N726 P19Arf_N
NM_058197 NP_478104    

Related Sequences

 
mRNAGenPeptSwissProt
U26727 AAA82236 Q8N726
L27211 AAA92554 P42771
U38945 AAB01737 Q8N726
S78535 AAC60649 Q8N726
AF115544 AAD11437 P42771
BC015960 AAH15960 Q8N726
BC021998 AAH21998 Q8N726
BT007020 AAP35666 Q8N726
DQ318021 ABC47036 P42771
AJ844636 CAH59950 Q5ZEY9

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CDKN2A NP_000068 R.norvegicus Cdkn2a 25163   NP_113738 78
M.musculus Cdkn2a 12578 Gene Info NP_001035744 74

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta