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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. RRM2B, ribonucleotide reductase M2 B (TP53 inducible)
Sequence ID:NM_001172477
RefSeqGene ID:NG_016617
Entrez Gene ID:50484
Ensembl ID:ENSG00000048392

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:8q23.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 103216729 - 103251346

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6143754Full LengthBC108261ribonucleotide reductase M2 B (TP53 inducible)
40126047Full LengthBC117496ribonucleotide reductase M2 B (TP53 inducible)
40146659Full LengthBC130628ribonucleotide reductase M2 B (TP53 inducible)
3866681IncompleteBC042468ribonucleotide reductase M2 B (TP53 inducible)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_056528  

Protein Infomation

NM_001172477 NP_001165948      
NM_001172478 NP_001165949      
NM_015713 NP_056528 Q7LG56 EC Ribonuc_red_sm

Related Sequences

BC042468 AAH42468 Q7LG56 EC
BC108261 AAI08262 Q7LG56 EC
BC117496 AAI17497 Q7LG56 EC
BC130628 AAI30629 Q7LG56 EC
EU831715 ACE86549    
EU831630 ACE87230    
HQ258190 ADR82944    
AK001965 BAA92005 Q7LG56 EC
AB036063 BAA92434 Q7LG56 EC
AB163437 BAD11774 Q7LG56 EC
AB163438 BAD11775 Q7LG56 EC
AB166669 BAD12265 Q7LG56 EC
AB166670 BAD12266 Q7LG56 EC
AB166671 BAD12267 Q7LG56 EC
AK304354 BAG65196 B4E2N4  
AL137348 CAB70703 Q7LG56 EC
CR627376 CAH10473 Q6AI41  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens RRM2B NP_056528 R.norvegicus Rrm2b 299976   NP_001124015 94
M.musculus Rrm2b 382985 Gene Info NP_955770 93

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)