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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CD46, CD46 molecule, complement regulatory protein
Sequence ID:NM_002389
NM_172351
NM_172352
NM_172359
NM_153826
NM_172353
NM_172361
NM_172350
RefSeqGene ID:NG_009296
Entrez Gene ID:4179
Ensembl ID:ENSG00000117335

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
HEMOLYTIC UREMIC SYNDROME, ATYPICALCFH
CFHR1
CFHR3
CFI
HEMOLYTIC UREMIC SYNDROME, ATYPICAL 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 207925557 - 207933068

 Exon Info From UCSC:
NM_002389
NM_172351
NM_172352
NM_172359
NM_153826
NM_172353
NM_172361
NM_172350

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4823040Full LengthBC030594CD46 molecule, complement regulatory protein

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_758869  NP_758871  NP_758860  NP_758861  NP_722548  NP_758862  NP_002380  NP_758863  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002389 NP_002380 P15529 Sushi
NM_153826 NP_722548   Sushi
NM_172350 NP_758860   Sushi
NM_172351 NP_758861   Sushi
NM_172352 NP_758862   Sushi
NM_172353 NP_758863   Sushi
NM_172359 NP_758869   Sushi
NM_172361 NP_758871   Sushi

Related Sequences

 
mRNAGenPeptSwissProt
M58050 AAA62833 P15529
S51940 AAB24802 P15529
AF209712 AAF73844 P15529
AF209713 AAF73845 P15529
AF209714 AAF73846 P15529
BC030594 AAH30594 P15529
EF076055 ABK81635 P15529
EF076056 ABK81636 P15529
EF076057 ABK81637 P15529
EF076058 ABK81638 P15529
DQ890901 ABM81827  
DQ894054 ABM84980  
D84105 BAA12224 P15529
AK222822 BAD96542 P15529
AK291227 BAF83916 P15529
AK296819 BAG59392 B4DL30
A18585 CAA01400  
Y00651 CAA68675 P15529
Y07713 CAA68985 Q92494
BX537451 CAD97694 P15529
BX640613 CAE45719 P15529
BX649050 CAI45983 P15529

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CD46 NP_758869 R.norvegicus Cd46 29333   NP_062063 52
M.musculus Cd46 17221 Gene Info NP_034908 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)