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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ACTN1, Actinin, alpha 1
Sequence ID:NM_001130004
NM_001102
NM_001130005
RefSeqGene ID:NG_029480
Entrez Gene ID:87
Ensembl ID:ENSG00000072110

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q24|14q22-q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 69346678 - 69347629

 Exon Info From UCSC:
NM_001130004
NM_001102
NM_001130005

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3547017Full LengthBC003576actinin, alpha 1
4856734Full LengthBC015766actinin, alpha 1
40009911IncompleteBC127124actinin, alpha 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001093  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001102 NP_001093 P12814 efhand
CH
Spectrin
NM_001130004 NP_001123476    
NM_001130005 NP_001123477    

Related Sequences

 
mRNAGenPeptSwissProt
M95178 AAA51582 P12814
BC003576 AAH03576 P12814
BC015766 AAH15766 P12814
BC127124 AAI27125 A1L0V1
BT007207 AAP35871 P12814
DQ496098 ABF50047 P12814
DQ890778 ABM81704  
DQ895768 ABM86694  
EU716325 ACE62922 P12814
FJ410030 ACJ24535 B7TY16
AK098203 BAG53591 B3KUX9
AK294317 BAG57591 B4DFY0
AK295099 BAG58135 P12814
AK299362 BAG61357 B4DRP5
AK298496 BAH12801 B7Z565
X15804 CAA33803 P12814
X55187 CAA38970 P12814
BX248020 CAD62344 Q86TX4
AJ844628 CAH59747 Q5ZEZ4

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ACTN1 NP_001123476 R.norvegicus Actn1 81634   NP_112267 99
M.musculus Actn1 109711 Gene Info NP_598917 99
A.gambiae ACTN_ANOGA 1281675   XP_321625 70
D.melanogaster Actn 31166   NP_477485 70
C.elegans atn-1 179709   NP_506128 63

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta