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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. TGM1, transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)
Sequence ID:NM_000359
RefSeqGene ID:NG_007150
Entrez Gene ID:7051
Ensembl ID:ENSG00000092295

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ICHTHYOSIFORM ERYTHRODERMA, CONGENITAL, NONBULLOUS, 1ALOX12B
ALOXE3
ICHTHYOSIS, LAMELLAR, AUTOSOMAL RECESSIVE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 24718321 - 24732383

 Exon Info From UCSC:
NM_000359

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4747045Full LengthBC034699transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000350  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000359 NP_000350 P22735 EC 2.3.2.13 Transglut_N
Transglut_C
Transglut_core

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M55183 AAA59474 P22735 EC 2.3.2.13
M62925 AAA61166 P22735 EC 2.3.2.13
BC034699 AAH34699 P22735 EC 2.3.2.13
DQ891485 ABM82411    
EU176599 ABW03400    
JF419518 AEM23727 G1APU8  
D90287 BAA14329 P22735 EC 2.3.2.13
AK291350 BAF84039 A8K5N5  
AK315819 BAF98710 B0AZM8  
AK315828 BAF98719 B0AZN7  
AK315843 BAF98734 P22735 EC 2.3.2.13
AK299436 BAG61413 B4DRV1  
AK301652 BAG63129 B4DWR7  
X57974 CAA41040 P22735 EC 2.3.2.13

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TGM1 NP_000350 R.norvegicus Tgm1 60335   NP_113847 92
M.musculus Tgm1 21816 Gene Info NP_001155186 91
A.gambiae AgaP_AGAP009100 1280052   XP_319850 40
D.melanogaster Tg 34093   NP_609174 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)