Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SIRT4, sirtuin 4
Sequence ID:NM_012240
Entrez Gene ID:23409
Ensembl ID:ENSG00000089163

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:12q

Chromosomal Position (from UCSC)

Chromosomal Position:12: 120740162 - 120751045

NM_012240 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
158120740123120740180
59556120741363120741860
557851120750258120750552
8521209120750686120751043

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40036789Full LengthBC109319sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae)
40036792Full LengthBC109320sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_036372  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_012240 NP_036372 Q9Y6E7 SIR2

Related Sequences

 
mRNAGenPeptSwissProt
AF083109 AAD40852 Q9Y6E7
BC109319 AAI09320 Q9Y6E7
BC109320 AAI09321 Q9Y6E7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SIRT4 NP_036372 M.musculus Sirt4 75387 Gene Info NP_598521 87
R.norvegicus Sirt4 304539   NP_001100617 86
C.elegans sir-2.2 181455   NP_001024673 50
D.melanogaster Sirt4 31480   NP_572241 50
A.thaliana SRT2 830782   NP_001078550 46
C.elegans sir-2.3 185876   NP_510220 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)