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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FLT3, fms-related tyrosine kinase 3
Sequence ID:NM_004119
RefSeqGene ID:NG_007066
Entrez Gene ID:2322
Ensembl ID:ENSG00000122025

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
LEUKEMIA, ACUTE MYELOGENOUSARHGEF12
CBFB
CEBPA
CHIC2
ETV6
GATA2
GMPS
JAK2
KIT
LPP
MLF1
MLLT10
NPM1
NSD1
NUP214
PICALM
RUNX1
RUNX1
SH3GL1
TERT
WHSC1L1

Cytogenetic Location (from UniGene)

Cytogenetic Location:13q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:13: 28577929 - 28674703

 Exon Info From UCSC:
NM_004119

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8992066Full LengthBC126350fms-related tyrosine kinase 3
9052559Full LengthBC144039fms-related tyrosine kinase 3
9052560Full LengthBC144040fms-related tyrosine kinase 3
5272266IncompleteBC036028fms-related tyrosine kinase 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004110  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004119 NP_004110 P36888 EC 2.7.10.1 ig
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U02687 AAA18947 P36888 EC 2.7.10.1
L36162 AAA35487 P36888 EC 2.7.10.1
BC126350 AAI26351 P36888 EC 2.7.10.1
BC144039 AAI44040 P36888 EC 2.7.10.1
BC144040 AAI44041 P36888 EC 2.7.10.1
Z26652 CAA81393 P36888 EC 2.7.10.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FLT3 NP_004110 M.musculus Flt3 14255 Gene Info NP_034359 86
R.norvegicus Flt3 140635   NP_001094292 85

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta