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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. NAGLU, N-acetylglucosaminidase, alpha
Sequence ID:NM_000263
RefSeqGene ID:NG_011552
Entrez Gene ID:4669
Ensembl ID:ENSG00000108784

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MUCOPOLYSACCHARIDOSIS TYPE IIIB (SANFILIPPO B) 

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 40688267 - 40696466

NM_000263 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
17234068795040688672
7248714068941540689562
87210184069035640690502
101911044069068740690772
110513614069296740693223
136227804069504540696463

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6213852Full LengthBC053991N-acetylglucosaminidase, alpha-

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000254  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000263 NP_000254 P54802 EC 3.2.1.50 NAGLU

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U40846 AAB06188 P54802 EC 3.2.1.50
L78464 AAB36604 P54802 EC 3.2.1.50
U43573 AAC50513 P54802 EC 3.2.1.50
BC053991 AAH53991 P54802 EC 3.2.1.50

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NAGLU NP_000254 M.musculus Naglu 27419 Gene Info NP_038820 83
R.norvegicus Naglu 360630   XP_002727861 81
A.thaliana CYL1 831214   NP_196873 44
A.gambiae AgaP_AGAP011750 1280890   XP_320760 43
D.melanogaster CG13397 46386   NP_652045 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)