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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SOCS1, suppressor of cytokine signaling 1
Sequence ID:NM_003745
Entrez Gene ID:8651
Ensembl ID:ENSG00000185338

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:16p13.13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 11348273 - 11349289

NM_003745 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
111121134827311349384
111312161134993511350038

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100016379Full LengthBC153088suppressor of cytokine signaling 1
100015498BC148542suppressor of cytokine signaling 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003736  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003745 NP_003736 O15524
Q4JHT5
SH2
SOCS_box

Related Sequences

 
mRNAGenPeptSwissProt
U88326 AAB62401 O15524
Q4JHT5
BC148542 AAI48543  
BC153088 AAI53089  
AB000676 BAA21537 O15524
AB005043 BAA22431 O15524
Q4JHT5
AB000734 BAA23521 O15524
Q4JHT5
AK127621 BAG54535 Q4JHT5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SOCS1 NP_003736 M.musculus Socs1 12703 Gene Info NP_034026 96
R.norvegicus Socs1 252971   NP_665886 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta