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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. TBK1, TANK-binding kinase 1
Sequence ID:NM_013254
Entrez Gene ID:29110
Ensembl ID:ENSG00000183735

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q14.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 64849650 - 64895161

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4824988Full LengthBC034950TANK-binding kinase 1
3938647IncompleteBC009864TANK-binding kinase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_037386  

Protein Infomation

NM_013254 NP_037386 Q9UHD2 EC Pkinase

Related Sequences

AF191838 AAF05989 Q9UHD2 EC
AF174536 AAF69106 Q9UHD2 EC
BC034950 AAH34950 Q9UHD2 EC
AK002192 BAA92129 Q9UHD2 EC
AK291039 BAF83728 Q9UHD2 EC
AK303683 BAG64676 B4E164  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens TBK1 NP_037386 R.norvegicus Tbk1 299827   NP_001100256 95
M.musculus Tbk1 56480 Gene Info NP_062760 94
A.gambiae AgaP_AGAP009565 1278956   XP_318573 41
D.melanogaster ik2 35329   NP_724278 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)