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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SLC11A2, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
Sequence ID:NM_000617
RefSeqGene ID:NG_021139
Entrez Gene ID:4891
Ensembl ID:ENSG00000110911

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 51379776 - 51420142

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3160522Full LengthBC002592solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
5300266Full LengthBC100014solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000608  

Protein Infomation

NM_000617 NP_000608   Nramp
NM_001174125 NP_001167596    
NM_001174126 NP_001167597 P49281  
NM_001174127 NP_001167598    
NM_001174128 NP_001167599    
NM_001174129 NP_001167600    
NM_001174130 NP_001167601    

Related Sequences

L37347 AAA79219 P49281
AF046997 AAC18078 P49281
AF064484 AAC21459 P49281
BC002592 AAH02592 P49281
BC100014 AAI00015 P49281
GQ129269 ACT64403  
GQ129270 ACT64404  
AB004857 BAA24933 P49281
AB062284 BAB93467 P49281
AK094735 BAG52920 P49281
AK128640 BAG54706 B3KY44
AK296445 BAG59096 B4DK84
AK315987 BAH14358 B7Z9M2
AK316507 BAH14878 B4DK84
AJ493662 CAD38517 P49281

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SLC11A2 NP_001167596 M.musculus Slc11a2 18174 Gene Info NP_032758 92
R.norvegicus Slc11a2 25715   NP_037305 91
D.melanogaster Mvl 42490   NP_001163668 62
C.elegans smf-1 180939   NP_001024792 59
C.elegans smf-2 191766   NP_509131 58
C.elegans smf-3 177044   NP_500235 57
A.gambiae AgaP_AGAP012464 1275957   XP_315254 54
A.thaliana NRAMP2 841127   NP_175157 53
A.thaliana NRAMP3 816847   NP_179896 53
A.thaliana NRAMP4 836868   NP_201534 52
S.cerevisiae SMF2 856447   NP_011917 33

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)