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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PTGES3, Prostaglandin E synthase 3 (cytosolic)
Sequence ID:NM_006601
Entrez Gene ID:10728
Ensembl ID:ENSG00000110958

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q13.3|12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 57057135 - 57081781

NM_006601 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1911745705712657058281
117511995705855957058583
120012625705998757060049
126313525706405857064147
135314515706553257065630
145215215706652357066592
152216355706673557066848
163619325708178157082077

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2821965Full LengthBC003005prostaglandin E synthase 3 (cytosolic)
3683159IncompleteBC021167prostaglandin E synthase 3 (cytosolic)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006592  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_006601 NP_006592 Q15185 EC 5.3.99.3 CS

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L24804 AAA18537 Q15185 EC 5.3.99.3
BC003005 AAH03005 Q15185 EC 5.3.99.3
BC021167 AAH21167 Q15185 EC 5.3.99.3
DQ896710 ABM87709    
EU176396 ABW03847    
AK291945 BAF84634 Q15185 EC 5.3.99.3
AK098214 BAG53594 B3KUY2  
AK293139 BAG56687 B4DDC6  
AK295208 BAG58204 B4DHP2  
AK298147 BAG60423 B4DP11  
AK298160 BAG60433 B4DP21  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PTGES3 NP_006592 R.norvegicus Ptges3 362809   NP_001124461 99

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)