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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. BACE1, Beta-site APP-cleaving enzyme 1
Sequence ID:NM_012104
NM_138972
NM_138971
NM_138973
NM_001207048
NM_001207049
RefSeqGene ID:NG_029372
Entrez Gene ID:23621
Ensembl ID:ENSG00000186318

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:11q23.2-q23.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 117156416 - 117186953

 Exon Info From UCSC:
NM_012104
NM_138972
NM_138971
NM_138973

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5311572Full LengthBC036084beta-site APP-cleaving enzyme 1
6538154Full LengthBC065492beta-site APP-cleaving enzyme 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_036236  NP_620428  NP_620427  NP_620429  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001207048 NP_001193977      
NM_001207049 NP_001193978      
NM_012104 NP_036236 P56817 EC 3.4.23.46 Asp
NM_138971 NP_620427     Asp
NM_138972 NP_620428     Asp
NM_138973 NP_620429     Asp

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF190725 AAF04142 P56817 EC 3.4.23.46
AF200193 AAF13715 P56817 EC 3.4.23.46
AF200343 AAF17079 P56817 EC 3.4.23.46
AF201468 AAF18982 P56817 EC 3.4.23.46
AF204943 AAF26367 P56817 EC 3.4.23.46
AF161367 AAF28927 Q9P0D2  
BC036084 AAH36084 Q8IYC8  
BC065492 AAH65492 P56817 EC 3.4.23.46
AF338816 AAK38374 P56817 EC 3.4.23.46
AF338817 AAK38375 P56817 EC 3.4.23.46
AF324837 AAM54050    
AF527782 AAM92013 Q8N698  
DQ891509 ABM82435    
DQ894700 ABM85626    
AB032975 BAA86463 P56817 EC 3.4.23.46
AB050436 BAB40931 P56817 EC 3.4.23.46
AB050437 BAB40932 P56817 EC 3.4.23.46
AB050438 BAB40933 P56817 EC 3.4.23.46
AB089958 BAC81826 Q76KP0  
AB177847 BAD66825 Q5W9H2  
AK075049 BAG52056 B3KQJ4  
AK296015 BAH12238 B7Z3K2  
AK296535 BAH12380 B7Z3Z4  
AL833810 CAD38674 Q8NDU6  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens BACE1 NP_036236 M.musculus Bace1 23821 Gene Info NP_035922 96
R.norvegicus Bace1 29392   NP_062077 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)