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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PPME1, protein phosphatase methylesterase 1
Sequence ID:NM_001271593
Entrez Gene ID:51400
Ensembl ID:ENSG00000214517

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q13.4Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 73941829 - 73965748

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3536415Full LengthBC003046protein phosphatase methylesterase 1
6161935Full LengthBC050705protein phosphatase methylesterase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_057231  

Protein Infomation

NM_001271593 NP_001258522      
NM_016147 NP_057231 Q9Y570 EC Abhydrolase_1

Related Sequences

AF157028 AAD44976 Q9Y570 EC
AF111853 AAF16692 Q9Y570 EC
BC003046 AAH03046 Q9Y570 EC
BC050705 AAH50705 Q9Y570 EC
DQ892348 ABM83274    
DQ895778 ABM86704    
AK001381 BAA91661 Q9Y570 EC
AK123288 BAC85574 Q9Y570 EC
AK022725 BAG51108 Q9Y570 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PPME1 NP_057231 M.musculus Ppme1 72590 Gene Info NP_082568 98
R.norvegicus Ppme1 361613   XP_341892 98
A.gambiae AgaP_AGAP008336 1277646   XP_317121 53
A.thaliana AT4G10050 826596   NP_567350 52
D.melanogaster CG5068 39032   NP_648277 52
C.elegans B0464.9 181999   NP_499084 51
N.crassa NCU00954 3881315   XP_965147 46
S.pombe SPBP4H10.17c 2541371   NP_596191 43
S.cerevisiae PPE1 856474   NP_011942 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)