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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PDE2A, phosphodiesterase 2A, cGMP-stimulated
Sequence ID:NM_001143839
NM_001146209
NM_001243784
NM_002599
Entrez Gene ID:5138
Ensembl ID:ENSG00000186642

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:11q13.4Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 72287185 - 72353475

 Exon Info From UCSC:
NM_001143839
NM_001146209
NM_002599

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5285017Full LengthBC040974phosphodiesterase 2A, cGMP-stimulated

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002590  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001143839 NP_001137311      
NM_001146209 NP_001139681      
NM_001243784 NP_001230713      
NM_002599 NP_002590 O00408 EC 3.1.4.17 PDEase_I
GAF

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U67733 AAC51320 O00408 EC 3.1.4.17
BC040974 AAH40974 Q8IW54  
AY495087 AAS75513 O00408 EC 3.1.4.17
AY495088 AAS75514 Q5J792  
AK131525 BAD18664 Q6ZMR1  
AK312434 BAG35343 B2R646  
AK092278 BAG52517 B3KRV5  
AK095024 BAG52972 B3KT60  
AK295676 BAG58533 B4DIM1  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PDE2A NP_002590 M.musculus Pde2a 207728 Gene Info NP_001137320 94
R.norvegicus Pde2a 81743   NP_001137319 93
A.gambiae AgaP_AGAP008304 1277681   XP_317162 51
C.elegans pde-2 176270   NP_001022706 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta