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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. MAP3K11, mitogen-activated protein kinase kinase kinase 11
Sequence ID:NM_002419
Entrez Gene ID:4296
Ensembl ID:ENSG00000173327

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone marrow, brain, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q13.1-q13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 65365228 - 65375893

NM_002419 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
38756536522665366098
87612506536686465367238
125113426537323165373322
134314786537341665373551
147915926537416165374274
159318366537474065374983
183720126537511165375286
201321616537539265375540
216223426537573865375918
234335746538048865381719

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4215281Full LengthBC011263mitogen-activated protein kinase kinase kinase 11
5733866Full LengthBC064543mitogen-activated protein kinase kinase kinase 11

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002410  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002419 NP_002410 Q16584 EC 2.7.11.25 SH3_1
Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U07747 AAA19647 Q16584 EC 2.7.11.25
L32976 AAA59859 Q16584 EC 2.7.11.25
BC011263 AAH11263 Q16584 EC 2.7.11.25
BC064543 AAH64543 Q16584 EC 2.7.11.25
AB209655 BAD92892 Q16584 EC 2.7.11.25
AK222781 BAD96501 Q16584 EC 2.7.11.25
AK315557 BAG37933 B2RDI6  
AK057256 BAG51893 B3KQ31  
AK090614 BAG52196 B3KQY4  
AK299609 BAG61538 B4DS76  
AK316032 BAH14403 B4DS76  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MAP3K11 NP_002410 M.musculus Map3k11 26403 Gene Info NP_071295 95
R.norvegicus Map3k11 309168   NP_001013168 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta