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Gene Info

Gene Information For:Hs. NDUFS3, NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
Sequence ID:NM_004551
RefSeqGene ID:NG_011946
Entrez Gene ID:4722
Ensembl ID:ENSG00000213619

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
LEIGH SYNDROMEBCS1L
COX15
DLD
FOXRED1
NDUFA10
NDUFA12
NDUFA2
NDUFA9
NDUFAF2
NDUFAF6
NDUFS4
NDUFS7
NDUFS8
NDUFV1
SDHA
SURF1

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p11.11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 47600631 - 47606114

NM_004551 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11494760056147600709
1502154760082047600885
2163134760207647602173
3144634760238647602535
4645894760363947603764
5907094760390047604019
7109594760586547606114

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3346129Full LengthBC000617NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004542  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004551 NP_004542 O75489 EC 1.6.99.3
EC 1.6.5.3
Complex1_30kDa

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF067139 AAC27451 O75489 EC 1.6.99.3
EC 1.6.5.3
AF100743 AAD40386 O75489 EC 1.6.99.3
EC 1.6.5.3
BC000617 AAH00617 O75489 EC 1.6.99.3
EC 1.6.5.3
DQ891934 ABM82860    
DQ895121 ABM86047    
AK223255 BAD96975 Q53FM7  
AK313802 BAG36538 O75489 EC 1.6.99.3
EC 1.6.5.3
AK294167 BAG57489 B4DFM8  
AL135819 CAB63881 Q9UF24  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NDUFS3 NP_004542 M.musculus Ndufs3 68349 Gene Info NP_080964 88
R.norvegicus Ndufs3 295923   NP_001099959 86
M.musculus Gm12251 624814 Gene Info XP_894449 85
A.gambiae AgaP_AGAP006456 1277067   XP_316497 70
D.melanogaster CG12079 38378   NP_647775 67
A.thaliana nad9 814568   NP_085479 62
C.elegans nuo-2 172363   NP_491881 59
N.crassa NCU04074 3873779   XP_957689 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)