Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CACNA1A, calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Sequence ID:NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
RefSeqGene ID:NG_011569
Entrez Gene ID:773
Ensembl ID:ENSG00000141837

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
EPISODIC ATAXIA, TYPE2 
MIGRAINE, FAMILIAL HEMIPLEGIC, 1 
SPINOCEREBELLAR ATAXIA 6 

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 13318268 - 13617073

 Exon Info From UCSC:
NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000059  NP_075461  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000068 NP_000059   Ion_trans
PKD_channel
NM_001127221 NP_001120693    
NM_001127222 NP_001120694    
NM_001174080 NP_001167551    
NM_023035 NP_075461   Ion_trans
PKD_channel

Related Sequences

 
mRNAGenPeptSwissProt
S76537 AAB33068 O00555
U79663 AAB49674 O00555
U79664 AAB49675 O00555
U79665 AAB49676 O00555
U79667 AAB49677 O00555
U79668 AAB49678 O00555
AF004883 AAB61612 O00555
AF004884 AAB61613 O00555
U79666 AAB64179 O00555
AF100774 AAC77460 O95387
FJ040507 ACH89974 B5TYJ1
AB035726 BAA94765 Q9NS89
AB035727 BAA94766 Q9NS88
X99897 CAA68172 O00555

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CACNA1A NP_075461 M.musculus Cacna1a 12286 Gene Info NP_031604 93
R.norvegicus Cacna1a 25398   NP_037050 92
D.melanogaster cac 32158   NP_001014732 63
A.gambiae AgaP_AGAP002578 1273390   XP_312358 61
C.elegans unc-2 180570   NP_001123176 56

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)