Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. UROS, uroporphyrinogen III synthase
Sequence ID:NM_000375
RefSeqGene ID:NG_011557
Entrez Gene ID:7390
Ensembl ID:ENSG00000188690

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q25.2-q26.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 127477151 - 127505201

NM_000375 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3160463Full LengthBC002573uroporphyrinogen III synthase
3631945IncompleteBC004338uroporphyrinogen III synthase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000366  

Protein Infomation

NM_000375 NP_000366 P10746 EC HEM4

Related Sequences

J03824 AAA60273 P10746 EC
AF230665 AAG36795 P10746 EC
BC002573 AAH02573 P10746 EC
BC004338 AAH04338 Q9BT54  
DQ891936 ABM82862    
DQ895123 ABM86049    
AK314896 BAG37410 P10746 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens UROS NP_000366 M.musculus Uros 22276 Gene Info NP_033505 78
R.norvegicus Uros 309070   NP_001012068 78
D.melanogaster CG1885 31817   NP_572507 39
A.gambiae AgaP_AGAP008064 1277887   XP_317395 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta