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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. HTRA1, HtrA serine peptidase 1
Sequence ID:NM_002775
RefSeqGene ID:NG_011554
Entrez Gene ID:5654
Ensembl ID:ENSG00000166033

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, lung, lymph node, lymphoreticular, mammary gland, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q26.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 124248962 - 124274423

NM_002775 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1600124221040124221639
601700124248417124248516
701905124248937124249141
9061100124266206124266400
11011133124266885124266917
11341248124268171124268285
12491306124269611124269668
13071402124271485124271580
14032120124273706124274423

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100069230Full LengthBC172536HtrA serine peptidase 1
4177882IncompleteBC011352HtrA serine peptidase 1
5289018IncompleteBC031082HtrA serine peptidase 1
100063230BC156552HtrA serine peptidase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002766  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002775 NP_002766 Q92743 Trypsin
PDZ
Kazal_2

Related Sequences

 
mRNAGenPeptSwissProt
AF097709 AAC97211 Q92743
BC011352 AAH11352 Q05DJ8
BC156552 AAI56553  
BC172536 AAI72536  
D87258 BAA13322 Q92743
AK290089 BAF82778 A8K224
AK091944 BAG52446 B3KRN4
AK092476 BAG52557 A8K224
Y07921 CAA69226 Q92743

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HTRA1 NP_002766 M.musculus Htra1 56213 Gene Info NP_062510 92
R.norvegicus Htra1 65164   NP_113909 92

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)