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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FBXW4, F-box and WD repeat domain containing 4
Sequence ID:NM_022039
RefSeqGene ID:NG_008091
Entrez Gene ID:6468
Ensembl ID:ENSG00000107829

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, brain, cartilage, cerebellum, cerebrum, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 103370422 - 103455016

NM_022039 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
93838103370421103371166
839980103371384103371525
9811121103372093103372233
11221187103384501103384566
11881282103427642103427736
12831415103432671103432803
14161601103433244103433429
16021697103436097103436192
16982303103454137103454742

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5223794Full LengthBC063415F-box and WD repeat domain containing 4
3641604IncompleteBC007380F-box and WD repeat domain containing 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_071322  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_022039 NP_071322 P57775 WD40
F-box

Related Sequences

 
mRNAGenPeptSwissProt
AF281859 AAG22739 P57775
BC007380 AAH07380 P57775
BC063415 AAH63415 P57775
AK314735 BAG37276 B2RBM9

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FBXW4 NP_071322 R.norvegicus Fbxw4 309444   NP_001101070 93
M.musculus Fbxw4 30838 Gene Info NP_038935 92

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)