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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ALDH18A1, aldehyde dehydrogenase 18 family, member A1
Sequence ID:NM_001017423
NM_002860
RefSeqGene ID:NG_012258
Entrez Gene ID:5832
Ensembl ID:ENSG00000059573

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CUTIS LAXA, AUTOSOMAL RECESSIVE, TYPE IIIA 

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q24.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 97365699 - 97416416

 Exon Info From UCSC:
NM_001017423
NM_002860

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6156087Full LengthBC106054aldehyde dehydrogenase 18 family, member A1
9052448Full LengthBC143930aldehyde dehydrogenase 18 family, member A1
40125791Full LengthBC117240aldehyde dehydrogenase 18 family, member A1
40125793Full LengthBC117242aldehyde dehydrogenase 18 family, member A1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002851  NP_001017423  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001017423 NP_001017423     AA_kinase
NM_002860 NP_002851 P54886 EC 2.7.2.11
EC 1.2.1.41
AA_kinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U68758 AAD00169 P54886 EC 2.7.2.11
EC 1.2.1.41
U76542 AAD17454 P54886 EC 2.7.2.11
EC 1.2.1.41
BC106054 AAI06055 P54886 EC 2.7.2.11
EC 1.2.1.41
BC117240 AAI17241 P54886 EC 2.7.2.11
EC 1.2.1.41
BC117242 AAI17243 P54886 EC 2.7.2.11
EC 1.2.1.41
BC143930 AAI43931 P54886 EC 2.7.2.11
EC 1.2.1.41
HQ258499 ADR83253    
AK312271 BAG35201 P54886 EC 2.7.2.11
EC 1.2.1.41
AK295487 BAH12086 P54886 EC 2.7.2.11
EC 1.2.1.41
AK299557 BAH13064 P54886 EC 2.7.2.11
EC 1.2.1.41
X94453 CAA64224 P54886 EC 2.7.2.11
EC 1.2.1.41

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ALDH18A1 NP_002851 M.musculus Aldh18a1 56454 Gene Info NP_062672 96
R.norvegicus Aldh18a1 361755   NP_001101994 95
A.gambiae AgaP_AGAP002518 1273445   XP_312421 60
D.melanogaster CG7470 40443   NP_649375 60
C.elegans T22H6.2 181417   NP_510133 57
A.thaliana P5CS1 818566   NP_001189714 49
A.thaliana P5CS2 824727   NP_191120 49
N.crassa NCU01412 3876982   XP_960835 46
S.cerevisiae PRO2 854501   NP_014968 44
S.pombe pro1 2543410   NP_593164 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)