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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. P4HA1, prolyl 4-hydroxylase, alpha polypeptide I
Sequence ID:NM_000917
NM_001017962
NM_001142595
NM_001142596
Entrez Gene ID:5033
Ensembl ID:ENSG00000122884

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, soft tissue, stem cell, stomach, synovium, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q21.3-q23.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 74769744 - 74772255

 Exon Info From UCSC:
NM_000917
NM_001017962
NM_001142595
NM_001142596

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4797051Full LengthBC034998prolyl 4-hydroxylase, alpha polypeptide I

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000908  NP_001017962  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000917 NP_000908 Q5VSQ6   2OG-FeII_Oxy
TPR_2
P4Ha_N
NM_001017962 NP_001017962 P13674 EC 1.14.11.2 2OG-FeII_Oxy
TPR_2
P4Ha_N
NM_001142595 NP_001136067      
NM_001142596 NP_001136068      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M24486 AAA36534 P13674 EC 1.14.11.2
M24487 AAA36535 P13674 EC 1.14.11.2
BC034998 AAH34998 P13674 EC 1.14.11.2
DQ891669 ABM82595    
DQ894855 ABM85781    
AK222960 BAD96680 Q5VSQ6  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens P4HA1 NP_001017962 M.musculus P4ha1 18451 Gene Info NP_035160 95
R.norvegicus P4ha1 64475   NP_742059 94
A.gambiae AgaP_AGAP000971 1270466   XP_309164 51
D.melanogaster PH4alphaEFB 43620   NP_733371 50
C.elegans phy-2 178170   NP_502317 48
C.elegans dpy-18 176569   NP_499464 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)