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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SGPL1, sphingosine-1-phosphate lyase 1
Sequence ID:NM_003901
Entrez Gene ID:8879
Ensembl ID:ENSG00000166224

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:10q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 72575725 - 72640930

 Exon Info From UCSC:
NM_003901

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6150776Full LengthBC052991sphingosine-1-phosphate lyase 1
3357509IncompleteBC041567sphingosine-1-phosphate lyase 1
6253152IncompleteBC051238sphingosine-1-phosphate lyase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003892  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_003901 NP_003892 O95470 EC 4.1.2.27 Pyridoxal_deC

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF144638 AAD44755 O95470 EC 4.1.2.27
BC052991 AAH52991 O95470 EC 4.1.2.27
AB033078 BAA86566 O95470 EC 4.1.2.27
AK314615 BAG37181 O95470 EC 4.1.2.27
AJ011304 CAA09590 O95470 EC 4.1.2.27

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SGPL1 NP_003892 R.norvegicus Sgpl1 286896   NP_775139 86
M.musculus Sgpl1 20397 Gene Info NP_033189 85
A.gambiae AgaP_AGAP001724 1281450   XP_321361 50
D.melanogaster Sply 46059   NP_725652 50
N.crassa NCU06761 3879657   XP_963533 50
A.thaliana DPL1 839691   NP_174119 44
S.cerevisiae DPL1 851888   NP_010580 43
C.elegans tag-38 181859   NP_505372 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)