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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SGPL1, sphingosine-1-phosphate lyase 1
Sequence ID:NM_003901
Entrez Gene ID:8879
Ensembl ID:ENSG00000166224

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 72575725 - 72640930

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6150776Full LengthBC052991sphingosine-1-phosphate lyase 1
3357509IncompleteBC041567sphingosine-1-phosphate lyase 1
6253152IncompleteBC051238sphingosine-1-phosphate lyase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003892  

Protein Infomation

NM_003901 NP_003892 O95470 EC Pyridoxal_deC

Related Sequences

AF144638 AAD44755 O95470 EC
BC052991 AAH52991 O95470 EC
AB033078 BAA86566 O95470 EC
AK314615 BAG37181 O95470 EC
AJ011304 CAA09590 O95470 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SGPL1 NP_003892 R.norvegicus Sgpl1 286896   NP_775139 86
M.musculus Sgpl1 20397 Gene Info NP_033189 85
A.gambiae AgaP_AGAP001724 1281450   XP_321361 50
D.melanogaster Sply 46059   NP_725652 50
N.crassa NCU06761 3879657   XP_963533 50
A.thaliana DPL1 839691   NP_174119 44
S.cerevisiae DPL1 851888   NP_010580 43
C.elegans tag-38 181859   NP_505372 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)