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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. MARCH8, Membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
Sequence ID:NM_001002265
Entrez Gene ID:220972
Ensembl ID:ENSG00000165406

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q11.21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 45950032 - 45952247

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4830278Full LengthBC025394membrane-associated ring finger (C3HC4) 8
5267214Full LengthBC066988membrane-associated ring finger (C3HC4) 8

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_659458  NP_001002265  NP_001002266  

Protein Infomation

NM_001002265 NP_001002265 Q5T0T0 zf-C3HC4
NM_001002266 NP_001002266 Q5T0T0 zf-C3HC4
NM_145021 NP_659458 Q5T0T0 zf-C3HC4

Related Sequences

BC025394 AAH25394 Q5T0T0
BC066988 AAH66988 Q5T0T0
AK313340 BAG36144 Q5T0T0

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MARCH8 NP_659458 M.musculus March8 71779 Gene Info NP_082196 93
R.norvegicus March8 312656   NP_001101352 93

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)