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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. DHCR24, 24-dehydrocholesterol reductase
Sequence ID:NM_014762
RefSeqGene ID:NG_008839
Entrez Gene ID:1718
Ensembl ID:ENSG00000116133

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
DESMOSTEROLOSIS 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p32.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 55315305 - 55352849

NM_014762 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
127605531529955318058
276129395531910655319284
294031375531970955319906
313832815533097555331118
328235455533702255337285
354636645534076555340883
366537705534161455341719
377139265534929055349445
392742865535256155352920

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3638639Full LengthBC00437524-dehydrocholesterol reductase
4130396Full LengthBC01166924-dehydrocholesterol reductase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_055577  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_014762 NP_055577 Q15392 EC 1.3.1.72 FAD_binding_4

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF261758 AAG17288 Q15392 EC 1.3.1.72
BC004375 AAH04375 Q15392 EC 1.3.1.72
BC011669 AAH11669 Q15392 EC 1.3.1.72
DQ893405 ABM84331    
DQ896723 ABM87722    
D13643 BAA02806 Q15392 EC 1.3.1.72
AB073391 BAE45721 Q3LIE7  
AK298414 BAH12782 B7Z546  
AK302774 BAH13803 B7Z817  
AK304302 BAH14155 B7Z919  
AK304421 BAH14179 B7Z943  
AK304437 BAH14186 Q3LIE7  
AK316419 BAH14790 B7ZAV4  
AK316427 BAH14798 Q3LIE7  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DHCR24 NP_055577 M.musculus Dhcr24 74754 Gene Info NP_444502 97
R.norvegicus Dhcr24 298298   NP_001073617 97
C.elegans F52H2.6 186134   NP_508463 51
A.thaliana DWF1 821519   NP_001189937 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)