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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. EPRS, glutamyl-prolyl-tRNA synthetase
Sequence ID:NM_004446
Entrez Gene ID:2058
Ensembl ID:ENSG00000136628

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q41Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 220160632 - 220219872

 Exon Info From UCSC:
NM_004446

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8991991Full LengthBC126275glutamyl-prolyl-tRNA synthetase
9020454Full LengthBC136465glutamyl-prolyl-tRNA synthetase
3887698IncompleteBC015494glutamyl-prolyl-tRNA synthetase
4997672IncompleteBC034797glutamyl-prolyl-tRNA synthetase
5737489IncompleteBC046156glutamyl-prolyl-tRNA synthetase
6153037IncompleteBC105983glutamyl-prolyl-tRNA synthetase
6172759IncompleteBC058921glutamyl-prolyl-tRNA synthetase
30347635IncompleteBC067841glutamyl-prolyl-tRNA synthetase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004437  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004446 NP_004437 P07814 EC 6.1.1.15
EC 6.1.1.17
WHEP-TRS
tRNA-synt_2b
tRNA-synt_1c
HGTP_anticodon
tRNA-synt_1c_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC015494 AAH15494 P07814 EC 6.1.1.15
EC 6.1.1.17
BC034797 AAH34797 P07814 EC 6.1.1.15
EC 6.1.1.17
BC046156 AAH46156 P07814 EC 6.1.1.15
EC 6.1.1.17
BC058921 AAH58921 P07814 EC 6.1.1.15
EC 6.1.1.17
BC105983 AAI05984 Q3KQZ8  
BC126275 AAI26276 P07814 EC 6.1.1.15
EC 6.1.1.17
BC136465 AAI36466 P07814 EC 6.1.1.15
EC 6.1.1.17
AY493416 AAS72877 P07814 EC 6.1.1.15
EC 6.1.1.17
JQ080075 AFA28127 H6WCP5  
AK296755 BAG59337 B4DKX5  
AK298192 BAG60462 B4DP50  
X07466 CAA30354 P07814 EC 6.1.1.15
EC 6.1.1.17
X54326 CAA38224 P07814 EC 6.1.1.15
EC 6.1.1.17
CR933648 CAI45949 P07814 EC 6.1.1.15
EC 6.1.1.17

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EPRS NP_004437 M.musculus Eprs 107508 Gene Info NP_084011 89
R.norvegicus Eprs 289352   NP_001019409 88
S.cerevisiae GUS1 852606   NP_011269 48
S.pombe SPAC17A5.15c 2542408   NP_593483 48
A.thaliana AT5G26710 832718   NP_850874 44
N.crassa NCU08894 3874979   XP_958832 44
P.falciparum PF13_0257 814222   XP_001350205 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)