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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. NOTCH1, Notch 1
Sequence ID:NM_017617
RefSeqGene ID:NG_007458
Entrez Gene ID:4851
Ensembl ID:ENSG00000148400

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
AORTIC VALVE DISEASE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:9q34.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 139388896 - 139411815

 Exon Info From UCSC:
NM_017617

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_060087  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_017617 NP_060087 P46531 EGF
Ank
Laminin_EGF
Notch
DSL
EGF_alliinase
NOD
EGF_CA
NODP
EGF_2

Related Sequences

 
mRNAGenPeptSwissProt
M73980 AAA60614 P46531
AF308602 AAG33848 P46531
AK000012 BAA90883 Q9NXX4
AB209873 BAD93110 P46531
CR457221 CAG33502 Q6IAD4

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NOTCH1 NP_060087 M.musculus Notch1 18128 Gene Info NP_032740 92
R.norvegicus Notch1 25496   NP_001099191 92
A.gambiae AgaP_AGAP001015 1270506   XP_309208 53
D.melanogaster N 31293   NP_476859 49

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta