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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PTGES2, prostaglandin E synthase 2
Sequence ID:NM_001256335
NM_025072
NM_198938
NM_198939
NM_198940
NR_027812
RefSeqGene ID:NG_012488
Entrez Gene ID:80142
Ensembl ID:ENSG00000148334

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:9q34.11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 130882972 - 130890008

Transcript StartTranscript EndChromosomal Start Chromosomal End
58637130882972130883551
638755130884640130884757
756956130885212130885412
9571106130885980130886129
11071165130886770130886828
11661363130887522130887719
13642120130889717130890473

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3946495Full LengthBC011613prostaglandin E synthase 2
3536456IncompleteBC009456prostaglandin E synthase 2
4134979IncompleteBC009397prostaglandin E synthase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_945176  NP_079348  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001256335 NP_001243264      
NM_025072 NP_079348 Q9H7Z7 EC 5.3.99.3 GST_C
Glutaredoxin
NM_198938 NP_945176     GST_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC009397 AAH09397 Q9H7Z7 EC 5.3.99.3
BC009456 AAH09456 Q9H7Z7 EC 5.3.99.3
BC011613 AAH11613 Q9H7Z7 EC 5.3.99.3
DQ891904 ABM82830    
DQ895090 ABM86016    
AK024100 BAB14826 Q9H7Z7 EC 5.3.99.3
AK223520 BAD97240 Q9H7Z7 EC 5.3.99.3
AK057049 BAG51854 B3KPZ2  
AK301618 BAG63103 B4DWP1  
AM392565 CAL37443    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PTGES2 NP_079348 M.musculus Ptges2 96979 Gene Info NP_598544 84
R.norvegicus Ptges2 311865   NP_001101302 84
A.thaliana AT5G42150 834220   NP_199030 49
A.gambiae AgaP_AGAP004992 1275818   XP_315097 47
C.elegans R11A8.5 177925   NP_501913 47
D.melanogaster Su(P) 39856   NP_524116 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)