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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PFN1, profilin 1
Sequence ID:NM_005022
RefSeqGene ID:NG_032945
Entrez Gene ID:5216
Ensembl ID:ENSG00000108518

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 4849194 - 4851825

NM_005022 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2900010Full LengthBC006768profilin 1
3349355Full LengthBC002475profilin 1
3890384Full LengthBC015164profilin 1
3896948Full LengthBC013439profilin 1
30337970Full LengthBC057828profilin 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005013  

Protein Infomation

NM_005022 NP_005013 P07737 Profilin

Related Sequences

J03191 AAA36486 P07737
BC002475 AAH02475 P07737
BC006768 AAH06768 P07737
BC013439 AAH13439 P07737
BC015164 AAH15164 P07737
BC057828 AAH57828 P07737
BT007001 AAP35647 P07737
DQ891100 ABM82026  
DQ894282 ABM85208  
GU727630 ADU87632 P07737
D28377 BAA05743  
AK312168 BAG35102 P07737
CR407670 CAG28598 P07737

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PFN1 NP_005013 M.musculus Pfn1 18643 Gene Info NP_035202 96
R.norvegicus Pfn1 64303   NP_071956 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta