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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PTCH1, patched 1
Sequence ID:NM_000264
NM_001083602
NM_001083603
NM_001083604
NM_001083605
NM_001083606
NM_001083607
RefSeqGene ID:NG_007664
Entrez Gene ID:5727
Ensembl ID:ENSG00000185920

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
BASAL CELL CARCINOMA, SOMATICPTCH2
RASA1
BASAL CELL NEVUS SYNDROME 
HOLOPROSENCEPHALY-7 
MEDULLOBLASTOMAABR
APC
APC
BRCA2
CTNNB1
DMBT1
PTCH2
SUFU

Cytogenetic Location (from UniGene)

Cytogenetic Location:9q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 98242342 - 98279247

 Exon Info From UCSC:
NM_000264
NM_001083602
NM_001083603
NM_001083604
NM_001083605
NM_001083606
NM_001083607

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100016192BC152919patched homolog 1 (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000255  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000264 NP_000255 Q13635 Patched
NM_001083602 NP_001077071    
NM_001083603 NP_001077072    
NM_001083604 NP_001077073    
NM_001083605 NP_001077074    
NM_001083606 NP_001077075    
NM_001083607 NP_001077076    

Related Sequences

 
mRNAGenPeptSwissProt
U43148 AAC50496 Q13635
U59464 AAC50550 Q13635
BC043542 AAH43542 Q13635
BC152919 AAI52920  
AK124593 BAC85893 Q6ZVG8
AB189436 BAD74184 Q13635
AB189437 BAD74185 Q13635
AB189438 BAD74186 Q13635
AB189439 BAD74187 Q13635
AB189440 BAD74188 Q13635
AB209495 BAD92732 Q59FG5
AB214500 BAE45300 Q3LG18
AB233422 BAE45302 Q3LFT4
AB233423 BAE45303 Q3LFT3
AB233424 BAE45304 Q3LFT2
AB212828 BAF47711 A3KBF6
AB239329 BAF47712 Q13635

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PTCH1 NP_000255 M.musculus Ptch1 19206 Gene Info NP_032983 97
R.norvegicus Ptch1 89830   NP_446018 97
A.gambiae AgaP_AGAP011395 1278302   XP_317925 47
D.melanogaster ptc 35851   NP_523661 41
C.elegans ptc-1 174274   NP_495662 40
C.elegans ptc-3 173631   NP_494384 40
C.elegans ptc-2 191745   NP_495218 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta