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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. YWHAZ, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
Sequence ID:NM_001135699
NM_001135700
NM_001135701
NM_001135702
NM_003406
NM_145690
Entrez Gene ID:7534
Ensembl ID:ENSG00000164924

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:8q23.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 101946567 - 101949291

 Exon Info From UCSC:
NM_001135699
NM_001135700
NM_001135701
NM_001135702
NM_003406
NM_145690

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2988020Full LengthBC003623tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
3869494Full LengthBC108281tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
4793291Full LengthBC068456tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
5298373Full LengthBC099904tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
5563061Full LengthBC083508tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
6180974Full LengthBC063824tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
6315583Full LengthBC072426tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
8068989Full LengthBC101483tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
8327419Full LengthBC111951tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
5527579IncompleteBC051814tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
6504109IncompleteBC073141tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_663723  NP_003397  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001135699 NP_001129171    
NM_001135700 NP_001129172    
NM_001135701 NP_001129173    
NM_001135702 NP_001129174    
NM_003406 NP_003397 P63104 14-3-3
NM_145690 NP_663723 P63104 14-3-3

Related Sequences

 
mRNAGenPeptSwissProt
M86400 AAA36446 P63104
U28964 AAC52052 P63104
S79449 AAD14300 Q6LD62
BC003623 AAH03623 P63104
BC051814 AAH51814 P63104
BC063824 AAH63824 P63104
BC068456 AAH68456 P63104
BC072426 AAH72426 P63104
BC073141 AAH73141 P63104
BC083508 AAH83508 P63104
BC099904 AAH99904 P63104
BC101483 AAI01484 P63104
BC108281 AAI08282 P63104
BC111951 AAI11952 P63104
DQ185048 ABD14427 Q2F831
DQ891706 ABM82632  
DQ894884 ABM85810  
AK289945 BAF82634 P63104
AK315867 BAF98758 B0AZS6
AK294647 BAH11832 B7Z2E6
AK296902 BAH12451 B7Z465

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens YWHAZ NP_001129171 R.norvegicus Ywhaz 25578   NP_037143 100
M.musculus Ywhaz 22631 Gene Info NP_035870 100
C.elegans ftt-2 181348   NP_509939 82
D.melanogaster 14-3-3zeta 36059   NP_001014515 81
C.elegans par-5 178113   NP_502235 79
A.gambiae AgaP_AGAP007643 1269582   XP_001687869 79

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)