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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GDF6, growth differentiation factor 6
Sequence ID:NM_001001557
RefSeqGene ID:NG_008981
Entrez Gene ID:392255
Ensembl ID:ENSG00000156466

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
COLOBOMA, OCULARPAX6
PAX6
SHH

Cytogenetic Location (from UniGene)

Cytogenetic Location:8q22.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 97154557 - 97173020

NM_001001557 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1832109715455997157751
321137169717251497173019

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40132943Full LengthBC127947growth differentiation factor 6
40132947Full LengthBC127948growth differentiation factor 6
5295441IncompleteBC043222growth differentiation factor 6
100063013BC156445growth differentiation factor 6

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001001557  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001001557 NP_001001557 Q6KF10 TGF_beta
TGFb_propeptide

Related Sequences

 
mRNAGenPeptSwissProt
BC043222 AAH43222 Q6KF10
BC127947 AAI27948 A0PK22
BC127948 AAI27949 A0PK23
BC156445 AAI56446  
AJ537424 CAD60934 Q6KF10

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GDF6 NP_001001557 M.musculus Gdf6 242316 Gene Info NP_038554 88
R.norvegicus Gdf6 252834   NP_001013056 87

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)