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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. NBN, nibrin
Sequence ID:NM_002485
NM_001024688
RefSeqGene ID:NG_008860
Entrez Gene ID:4683
Ensembl ID:ENSG00000104320

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
NIJMEGEN BREAKAGE SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:8q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 90945713 - 90996840


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8860301Full LengthBC146797nibrin
9020792Full LengthBC136802nibrin
9020793Full LengthBC136803nibrin
3918702IncompleteBC108650nibrin
4104186IncompleteBC016762nibrin
100000683BC143065nibrin
100013542BC143066nibrin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002476  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002485 NP_002476 O60934 FHA
BRCT
Nbs1_N

Related Sequences

 
mRNAGenPeptSwissProt
AF051334 AAC39732 O60934
AF058696 AAC39752 O60934
BC016762 AAH16762 A0PJ71
BC108650 AAI08651 O60934
BC136802 AAI36803 O60934
BC136803 AAI36804 O60934
BC143065 AAI43066  
BC143066 AAI43067  
BC146797 AAI46798 A6H8Y5
AK223256 BAD96976 O60934
AK289848 BAF82537 A8K1D3
AK312410 BAG35323 O60934
BX640816 CAH56160 O60934

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NBN NP_002476 M.musculus Nbn 27354 Gene Info NP_038780 71
R.norvegicus Nbn 85482   NP_620228 70

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta