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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TERT, telomerase reverse transcriptase
Sequence ID:NM_001193376
NM_198253
NM_198254
NM_198255
RefSeqGene ID:NG_009265
Entrez Gene ID:7015
Ensembl ID:ENSG00000164362

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
APLASTIC ANEMIA 
APLASTICANEMIAIFNG
TERC
DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT 2 
LEUKEMIA, ACUTE MYELOGENOUSARHGEF12
CBFB
CEBPA
CHIC2
ETV6
FLT3
GATA2
GMPS
JAK2
KIT
LPP
MLF1
MLLT10
NPM1
NSD1
NUP214
PICALM
RUNX1
RUNX1
SH3GL1
WHSC1L1
PULMONARY FIBROSIS, IDIOPATHICELMOD2
MUC5B
SFTPA1
SFTPA1
SFTPA2
SFTPC
TERC

Cytogenetic Location (from UniGene)

Cytogenetic Location:5p15.33Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 1253842 - 1295104

 Exon Info From UCSC:
NM_001193376
NM_198253
NM_198255

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100069235Full LengthBC172541telomerase reverse transcriptase
5095305IncompleteBC062321telomerase reverse transcriptase
100061944BC156388telomerase reverse transcriptase

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001193376 NP_001180305      
NM_198253 NP_937983 O14746 EC 2.7.7.49  

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF043739 AAC40212    
AF015950 AAC51672 O14746 EC 2.7.7.49
AF018167 AAC51724 O14746 EC 2.7.7.49
BC156388 AAI56389    
BC172541 AAI72541    
JF896282 AEF12311 F6MZ67  
JF896285 AEF12312 F6MZ68  
AB085628 BAC11010 O14746 EC 2.7.7.49
AB086379 BAC11014 O14746 EC 2.7.7.49
AB086950 BAC11015 Q8NG38  
AX810036 CAE75638 O14746 EC 2.7.7.49
AX810378 CAE75644    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TERT NP_937983 M.musculus Tert 21752 Gene Info NP_033380 65
R.norvegicus Tert 301965   NP_445875 65
A.thaliana TERT 831548   NP_197187 29

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta