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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. EYA1, Eyes absent homolog 1 (Drosophila)
Sequence ID:NM_000503
NM_172058
NM_172059
NM_172060
RefSeqGene ID:NG_011735
Entrez Gene ID:2138
Ensembl ID:ENSG00000104313

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ANTERIOR SEGMENT ANOMALIES WITH OR WITHOUT CATARACT 
BRANCHIOOTIC SYNDROME 1 
OTOFACIOCERVICAL SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:8q13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 72111554 - 72268721

 Exon Info From UCSC:
NM_000503
NM_172058
NM_172059
NM_172060

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40084967Full LengthBC121799eyes absent homolog 1 (Drosophila)
40084971Full LengthBC121798eyes absent homolog 1 (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000494  NP_742057  NP_742056  NP_742055  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000503 NP_000494 Q99502 EC 3.1.3.48 Hydrolase
NM_172058 NP_742055 Q99502 EC 3.1.3.48 Hydrolase
NM_172059 NP_742056     Hydrolase
NM_172060 NP_742057     Hydrolase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC121798 AAI21799 Q0P517  
BC121799 AAI21800 Q99502 EC 3.1.3.48
AF467247 AAL73437 Q8WX80  
AK127798 BAG54573 B3KXR1  
AK295897 BAG58690 A6NCB9  
AJ000097 CAA03922 Q99502 EC 3.1.3.48
AJ000098 CAA03923 Q99502 EC 3.1.3.48

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EYA1 NP_000494 R.norvegicus Eya1 502935   XP_002729501 97
M.musculus Eya1 14048 Gene Info NP_034294 96
D.melanogaster eya 33916   NP_523492 59
A.gambiae AgaP_AGAP008726 1275576   XP_314837 56
A.thaliana EYA 818099   NP_565803 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)