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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PRKDC, protein kinase, DNA-activated, catalytic polypeptide
Sequence ID:NM_001081640
RefSeqGene ID:NG_023435
Entrez Gene ID:5591
Ensembl ID:ENSG00000253729

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:8q11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 48685675 - 48711953

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2900772IncompleteBC024963protein kinase, DNA-activated, catalytic polypeptide
4508982IncompleteBC037968protein kinase, DNA-activated, catalytic polypeptide

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_008835  

Protein Infomation

NM_001081640 NP_001075109      
NM_006904 NP_008835 P78527 EC PI3_PI4_kinase

Related Sequences

U35835 AAA79184 P78527 EC
U47077 AAB39925 P78527 EC
U34994 AAC50210 P78527 EC
AB208860 BAD92097 P78527 EC
AK296833 BAG59403 B4DL41  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PRKDC NP_008835 M.musculus Prkdc 19090 Gene Info NP_035289 79
R.norvegicus Prkdc 360748   NP_001101797 76
A.gambiae AgaP_AGAP003967 1278787   XP_318419 28

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta