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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PTK2B, PTK2B protein tyrosine kinase 2 beta
Sequence ID:NM_004103
NM_173174
NM_173175
NM_173176
RefSeqGene ID:NG_029510
Entrez Gene ID:2185
Ensembl ID:ENSG00000120899

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:8p21.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 27183085 - 27316186

 Exon Info From UCSC:
NM_004103
NM_173174
NM_173175
NM_173176

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4343040Full LengthBC042599PTK2B protein tyrosine kinase 2 beta
4824966Full LengthBC036651PTK2B protein tyrosine kinase 2 beta

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_775266  NP_004094  NP_775268  NP_775267  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004103 NP_004094 Q14289 EC 2.7.10.2 Focal_AT
Pkinase_Tyr
NM_173174 NP_775266 Q14289 EC 2.7.10.2 Focal_AT
Pkinase_Tyr
NM_173175 NP_775267     Pkinase
Focal_AT
Pkinase_Tyr
NM_173176 NP_775268 Q14289 EC 2.7.10.2 Focal_AT
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L49207 AAB47217 Q14289 EC 2.7.10.2
U43522 AAC05330 Q14289 EC 2.7.10.2
U33284 AAC50203 Q14289 EC 2.7.10.2
BC036651 AAH36651 Q14289 EC 2.7.10.2
BC042599 AAH42599 Q14289 EC 2.7.10.2
D45853 BAA08289 Q14289 EC 2.7.10.2
AK128371 BAC87404 Q6ZRA8  
AB209085 BAD92322 Q59GM4  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PTK2B NP_004094 R.norvegicus Ptk2b 50646   NP_059014 96
M.musculus Ptk2b 19229 Gene Info NP_001155838 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta