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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. COL1A2, collagen, type I, alpha 2
Sequence ID:NM_000089
RefSeqGene ID:NG_007405
Entrez Gene ID:1278
Ensembl ID:ENSG00000164692

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
EHLERS-DANLOS SYNDROME, CARDIAC VALVULAR FORM 
EHLERS-DANLOS SYNDROME, TYPE VIIACOL1A1
OI TYPE IICOL1A1
OI TYPE IIICOL1A1
OI TYPE IVCOL1A1
OSTEOPOROSISCALCR
COL1A1
IL6
LRP5
PDLIM4
VDR

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q22.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 94024206 - 94038136

 Exon Info From UCSC:
NM_000089

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4803351Full LengthBC042586collagen, type I, alpha 2
6474549Full LengthBC054498collagen, type I, alpha 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000080  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000089 NP_000080 P08123 Collagen
COLFI

Related Sequences

 
mRNAGenPeptSwissProt
M22816 AAA51844 P08123
J00114 AAA51996 P08123
S96821 AAB22020 P08123
S41099 AAB22761 P08123
J03464 AAB59374 P08123
L47668 AAB59577 P08123
BC042586 AAH42586 P08123
BC054498 AAH54498 P08123
AK297786 BAG60128 B4DN66
AK300194 BAG61967 B4DTF5
V00503 CAA23761 P08123
X02488 CAA26320 P08123
X55525 CAA39142 P08123
Y00724 CAA68709 P08123
Z74616 CAA98969 P08123

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens COL1A2 NP_000080 R.norvegicus Col1a2 84352   NP_445808 91
M.musculus Col1a2 12843 Gene Info NP_031769 90

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)