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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. ABCB1, ATP-binding cassette, sub-family B (MDR/TAP), member 1
Sequence ID:NM_000927
RefSeqGene ID:NG_011513
Entrez Gene ID:5243
Ensembl ID:ENSG00000085563

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q21.12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 87133179 - 87229465

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40146455Full LengthBC130424ATP-binding cassette, sub-family B (MDR/TAP), member 1

Protein Infomation

NM_000927 NP_000918 P08183 EC  

Related Sequences

M14758 AAA59575 P08183 EC
AF016535 AAB69423 P08183 EC
BC130424 AAI30425 A1L471  
AY425007 AAR83914 A8E2S6  
AY425005 AAR91621 Q6TBL4  
AY425006 AAR91622 Q6TBL4  
EU852583 ACF94687 A4D1D2  
EU854148 ACF94688 B5AK60  
AB208970 BAD92207 Q59GY9  
AK290159 BAF82848 P08183 EC
AM393352 CAL38230    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens ABCB1 NP_000918 R.norvegicus Abcb1a 170913   NP_596892 88
M.musculus Abcb1a 18671 Gene Info NP_035206 88
C.elegans pgp-9 180165   NP_507487 47
C.elegans pgp-1 178215   NP_502413 47
D.melanogaster Mdr50 36582   NP_523740 45
N.crassa NCU07546 3875197   XP_959059 44
S.pombe pmd1 2538709   NP_588265 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta