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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. OGDH, oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
Sequence ID:NM_001003941
RefSeqGene ID:NG_023260
Entrez Gene ID:4967
Ensembl ID:ENSG00000105953

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7p14-p13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 44664060 - 44747877

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3010095Full LengthBC014617oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
3528538Full LengthBC004964oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
40121616IncompleteBC128549oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
40121617IncompleteBC128550oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001003941  NP_002532  

Protein Infomation

NM_001003941 NP_001003941     E1_dh
NM_001165036 NP_001158508      
NM_002541 NP_002532 Q02218 EC E1_dh

Related Sequences

BC004964 AAH04964 Q02218 EC
BC009580 AAH09580 Q02218 EC
BC014617 AAH14617 Q02218 EC
BC128549 AAI28550 A2VCT2  
BC128550 AAI28551 A2VCT3  
DQ925674 ABL59901 A5XEI1  
DQ891880 ABM82806    
EU176648 ABW03449    
D10523 BAA01393 Q02218 EC
AK293871 BAG57261 B4DF00  
AK294951 BAG58026 B4DH65  
AK296400 BAG59067 B4DK55  
AK302805 BAG64007 B4DZ95  
AK304439 BAG65261 Q02218 EC
AK304690 BAG65461 B4E3E9  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens OGDH NP_002532 M.musculus Ogdh 18293 Gene Info NP_035086 96
R.norvegicus Ogdh 360975   NP_001017461 96
A.gambiae AgaP_AGAP006366 1276976   XP_001688858 66
D.melanogaster Nc73EF 39899   NP_788520 63
C.elegans T22B11.5 177235   NP_500617 59
A.thaliana AT5G65750 836704   NP_201376 53
A.thaliana AT3G55410 824707   NP_191101 52
S.cerevisiae KGD1 854681   NP_012141 48
S.pombe SPBC3H7.03c 2540991   NP_595772 48
N.crassa NCU05425 3879396   XP_963248 47
P.falciparum PF08_0045 2655496   XP_001349318 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)