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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. ICA1, Islet cell autoantigen 1, 69kDa
Sequence ID:NM_004968
Entrez Gene ID:3382
Ensembl ID:ENSG00000003147

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, synovium, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7p22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 8153403 - 8301780

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3854722Full LengthBC008640islet cell autoantigen 1, 69kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004959  NP_071682  

Protein Infomation

NM_001136020 NP_001129492    
NM_004968 NP_004959 Q6LCR0 Arfaptin
NM_022307 NP_071682 Q05084 ICA69

Related Sequences

L01100 AAA02564 Q05084
L21181 AAA64927 Q05084
U26591 AAB19033 Q05084
U26592 AAB19034 Q6LCT9
U37183 AAC50935 Q05084
U38260 AAC50936 Q6LCR0
BC008640 AAH08640 Q96HG3
DQ891505 ABM82431  
EU176613 ABW03414  
EU416199 ACB47390 B3FTQ2
AK292106 BAF84795 Q05084
AM393016 CAL37894  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens ICA1 NP_004959 M.musculus Ica1 15893 Gene Info NP_034622 90
R.norvegicus Ica1 81024   NP_110471 90
A.gambiae AgaP_AGAP006627 1277213   XP_316657 41
D.melanogaster CG10566 40331   NP_649283 40
C.elegans ric-19 191757   NP_491216 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)