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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PRKACB, protein kinase, cAMP-dependent, catalytic, beta
Sequence ID:NM_001242857
RefSeqGene ID:NG_029728
Entrez Gene ID:5567
Ensembl ID:ENSG00000142875

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p31.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 84630386 - 84704174

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3916100Full LengthBC016285protein kinase, cAMP-dependent, catalytic, beta
5262372Full LengthBC035058protein kinase, cAMP-dependent, catalytic, beta

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_997461  NP_002722  NP_891993  

Protein Infomation

NM_001242857 NP_001229786      
NM_001242858 NP_001229787      
NM_001242859 NP_001229788      
NM_001242860 NP_001229789      
NM_001242861 NP_001229790      
NM_001242862 NP_001229791      
NM_002731 NP_002722 P22694 EC Pkinase
NM_182948 NP_891993     Pkinase
NM_207578 NP_997461     Pkinase

Related Sequences

M34181 AAA60170 P22694 EC
BC016285 AAH16285 P22694 EC
BC035058 AAH35058 P22694 EC
AY927364 AAX19487 P22694 EC
AY927366 AAX19489 P22694 EC
AY927367 AAX19490 P22694 EC
AY927368 AAX19491 P22694 EC
EU832783 ACE87794    
EU832835 ACE87846    
EU832837 ACE87848    
EU832842 ACE87853    
GQ129231 ACT64365    
GQ129233 ACT64367    
GQ129248 ACT64382    
GQ129404 ACT64538    
AB209189 BAD92426 P22694 EC
AK314550 BAG37136 B2RB89  
AK091420 BAG52356 B1APG4  
AK296482 BAG59122 P22694 EC
AK304322 BAG65172 B4E2L0  
AK304375 BAG65213 P22694 EC
AB451239 BAG70053 B2RB89  
AB451364 BAG70178 B2RB89  
AK316115 BAH14486 B7ZA00  
BX537705 CAD97818 P22694 EC
BX641026 CAE46017 P22694 EC
CR936631 CAI56774 P22694 EC
AM392526 CAL37404    
AM393233 CAL38111    
AM393317 CAL38195    
AM393497 CAL38374    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PRKACB NP_891993 R.norvegicus Prkacb 293508   NP_001071113 97
M.musculus Prkacb 18749 Gene Info NP_001157672 92
D.melanogaster Pka-C1 34284   NP_723479 83
A.gambiae AgaP_AGAP001384 1281793   XP_321752 82
S.cerevisiae TPK2 855898   NP_015121 55
N.crassa NCU06240 3879246   XP_963091 55
S.pombe pka1 2539781   NP_595159 53

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta