Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PHGDH, phosphoglycerate dehydrogenase
Sequence ID:NM_006623
RefSeqGene ID:NG_009188
Entrez Gene ID:26227
Ensembl ID:ENSG00000092621

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 120279853 - 120286823

 Exon Info From UCSC:
NM_006623

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2820369Full LengthBC000303phosphoglycerate dehydrogenase
2961389Full LengthBC001349phosphoglycerate dehydrogenase
4156703Full LengthBC011262phosphoglycerate dehydrogenase
4662199IncompleteBC032110phosphoglycerate dehydrogenase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006614  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_006623 NP_006614 O43175 EC 1.1.1.95 2-Hacid_dh
2-Hacid_dh_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF171235 AAD51413 Q9UMY3  
AF171236 AAD51414 Q9UMY2  
AF171237 AAD51415 O43175 EC 1.1.1.95
BC000303 AAH00303 O43175 EC 1.1.1.95
BC001349 AAH01349 O43175 EC 1.1.1.95
BC011262 AAH11262 O43175 EC 1.1.1.95
BC032110 AAH32110 Q8N5M8  
DQ892073 ABM82999    
EU176546 ABW03347    
AK315360 BAG37755 O43175 EC 1.1.1.95
AK093306 BAG52685 B3KSC3  
CR456795 CAG33076 O43175 EC 1.1.1.95

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PHGDH NP_006614 M.musculus Phgdh 236539 Gene Info NP_058662 95
R.norvegicus Phgdh 58835   NP_113808 94
A.gambiae AgaP_AGAP008849 1279816   XP_319591 56
C.elegans C31C9.2 175012   NP_496868 54
D.melanogaster CG6287 34554   NP_609496 54
A.thaliana EDA9 829568   NP_195146 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)