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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SOD2, superoxide dismutase 2, mitochondrial
Sequence ID:NM_000636
NM_001024465
NM_001024466
RefSeqGene ID:NG_008729
Entrez Gene ID:6648
Ensembl ID:ENSG00000112096

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
MICROVASCULAR COMPLICATIONS OF DIABETES 6 

Cytogenetic Location (from UniGene)

Cytogenetic Location:6q25.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 160103196 - 160114273

 Exon Info From UCSC:
NM_000636
NM_001024465
NM_001024466

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3880111Full LengthBC012423superoxide dismutase 2, mitochondrial
4184203Full LengthBC016934superoxide dismutase 2, mitochondrial
3462291IncompleteBC001980superoxide dismutase 2, mitochondrial

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001019637  NP_001019636  NP_000627  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000636 NP_000627   Sod_Fe_N
Sod_Fe_C
NM_001024465 NP_001019636   Sod_Fe_N
Sod_Fe_C
NM_001024466 NP_001019637   Sod_Fe_N
Sod_Fe_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M36693 AAA36622 P04179 EC 1.15.1.1
BC012423 AAH12423 P04179 EC 1.15.1.1
BC016934 AAH16934 Q96AM7  
AY280718 AAP34407 Q7Z7M7  
AY280719 AAP34408 Q7Z7M6  
AY280720 AAP34409 Q7Z7M5  
AY280721 AAP34410 Q7Z7M4  
BT006967 AAP35613 P04179 EC 1.15.1.1
DQ003134 AAY21807 Q4ZJI1  
DQ893752 ABM84678    
DQ890587 ABM92204    
AK313082 BAG35908 P04179 EC 1.15.1.1
AK296809 BAG59382 P04179 EC 1.15.1.1
AK304766 BAG65521 B4E3K9  
X07834 CAA30687 P04179 EC 1.15.1.1
X14322 CAA32502 P04179 EC 1.15.1.1
X15132 CAA33228 P04179 EC 1.15.1.1
X59445 CAA42066 P04179 EC 1.15.1.1
Y00472 CAA68533 P04179 EC 1.15.1.1
Y00985 CAA68791 P04179 EC 1.15.1.1
AL050388 CAB62521 Q9UG59  
AM392836 CAL37714    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SOD2 NP_000627 M.musculus Sod2 20656 Gene Info NP_038699 90
R.norvegicus Sod2 24787   NP_058747 88
A.gambiae MNSOD1 1275254   XP_314490 66
C.elegans sod-2 172632   NP_492290 65
C.elegans sod-3 181748   NP_510764 63
D.melanogaster Sod2 36878   NP_476925 62
A.thaliana MSD1 820263   NP_187703 59
N.crassa NCU09560 3875632   XP_959485 55
S.pombe SPAC1486.01 2542886   NP_594089 52
S.cerevisiae SOD2 856399   NP_011872 49

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta