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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. NRAS, Neuroblastoma RAS viral (v-ras) oncogene homolog
Sequence ID:NM_002524
RefSeqGene ID:NG_007572
Entrez Gene ID:4893
Ensembl ID:ENSG00000213281

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, stem cell, stomach, synovium, t-cell, testis, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME TYPE IV 
COLON CANCERAKT1
APC
APC
AURKA
AXIN2
BCL10
BUB1B
CCND1
EP300
FGFR3
FLCN
MLH3
ODC1
PDGFRL
PIK3CA
PIK3CA
PLA2G2A
PTPRJ
SMAD7
TLR2
TLR4
TP53
TP53
NOONAN SYNDROME 6 
THYROID CARCINOMA, FOLLICULARHRAS
MINPP1
PTEN

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 115251155 - 115258781

NM_002524 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
23594115247078115250670
35953633115250774115250812
36343757115251151115251274
37583917115252189115252348
39184096115256420115256598
40974224115258670115258797
42254461115259278115259514

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3826638Full LengthBC005219neuroblastoma RAS viral (v-ras) oncogene homolog

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002515  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001007553 NP_001007554 O75534 CSD
NM_001130523 NP_001123995    
NM_001242891 NP_001229820    
NM_001242892 NP_001229821    
NM_001242893 NP_001229822    
NM_002524 NP_002515 P01111
Q5U091
Ras
NM_007158 NP_009089   CSD

Related Sequences

 
mRNAGenPeptSwissProt
AF070542 AAC28634 O75534
AF077054 AAD27787 O75534
BC005219 AAH05219 P01111
Q5U091
BC021692 AAH21692 Q8WU01
BC032446 AAH32446 O75534
AY049788 AAL15445 Q96L66
AF493919 AAM12633 P01111
Q5U091
BT019734 AAV38539 P01111
Q5U091
BT019735 AAV38540 P01111
Q5U091
AB020692 BAA74908 O75534
AK022516 BAB14073 Q9GZV0
AK022528 BAB14080 Q9GZV0
AK290146 BAF82835 O75534
X02751 CAA26529 P01111
Q5U091
AL050150 CAB43294 Q9UG93
AL110192 CAB53670 Q9UG12
CR749378 CAH18231 O75534
CR749431 CAH18269 Q68DF1
AM392858 CAL37736  
AM393166 CAL38044  
AM393479 CAL38356  
AM393616 CAL38492  
AM393624 CAL38500  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NRAS NP_002515 M.musculus Nras 18176 Gene Info NP_035067 99
R.norvegicus Nras 24605   NP_542944 99

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)