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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. MDM2, Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
Sequence ID:NM_002392
RefSeqGene ID:NG_016708
Entrez Gene ID:4193
Ensembl ID:ENSG00000135679

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, stem cell, stomach, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q14.3-q15Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 69202243 - 69233648

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100016457Full LengthBC153117Mdm2 p53 binding protein homolog (mouse)
100013443IncompleteBC152384Mdm2 p53 binding protein homolog (mouse)
100013452IncompleteBC152390Mdm2 p53 binding protein homolog (mouse)
100015531BC148522Mdm2 p53 binding protein homolog (mouse)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002383  

Protein Infomation

NM_002392 NP_002383 Q00987 zf-RanBP

Related Sequences

M92424 AAA60568 Q00987
U33199 AAA75514 Q00987
U33200 AAA75515 Q00987
U33201 AAA75516 Q00987
U33202 AAA75517 Q00987
U33203 AAA75518 Q00987
AF201370 AAF42995 Q00987
BC148522 AAI48523  
BC152384 AAI52385 A8WFP2
BC152390 AAI52391 A8WFP2
BC153117 AAI53118  
AF385322 AAL13242 Q96DS5
AF385323 AAL13243 Q96DS4
AF385324 AAL13244 Q96DS3
AF385325 AAL13245 Q96DS2
AF385326 AAL13246 Q96DS1
AF385327 AAL13247 Q96DS0
AF092843 AAL40178 Q8WYJ3
AF092844 AAL40179 Q00987
AF092845 AAL40180 Q00987
BT007258 AAP35922 Q00987
EU076746 ABT17083 A7UKX7
EU076747 ABT17084 A7UKX8
EU076748 ABT17085 A7UKX9
EU076749 ABT17086 A7UKY0
GQ848196 ACX31156 D0EKL1
JX015379 AFM80527 I6TMT1
JX015380 AFM80528 I6T4K8
JX015386 AFM80534 I6TZT4
JX015387 AFM80535 I6SST5
JX015389 AFM80537 I6TMU1
JX015390 AFM80538 I6T4L8
JX015391 AFM80539 I6TZT8
JX015392 AFM80540 I6SST9
AK290341 BAF83030 Q00987
AK312105 BAG35041 B2R594
Z12020 CAA78055 Q00987
AJ278975 CAC07809 Q9H4C5
AJ278976 CAC07810 Q9H4C4
AJ278977 CAC07811 Q9H4C3
AJ278978 CAC07812 Q9H4C2
AJ430612 CAD23251 Q8TE47
AJ430614 CAD23252 Q8TE46
AJ491698 CAD36959 Q8NDW2
AJ491699 CAD36960 Q8NDW1
AJ491700 CAD36961 Q8NDW0
AJ491701 CAD36962 Q8NDV9
AJ550516 CAD79455 Q9H4C2
AJ550517 CAD79456 Q86WA5
AJ550518 CAD79457 Q86WA4
AJ550519 CAD79458 Q86WA3
AJ550520 CAD79459 Q86WA2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MDM2 NP_002383 R.norvegicus Mdm2 314856   NP_001101569 84
M.musculus Mdm2 17246 Gene Info NP_034916 83

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta